P nervous system development 3.8e-18 6.2e-14
P system development 1.9e-16 1.5e-12
P multicellular organismal development 2.4e-15 1.3e-11
P organ development 6e-15 2.4e-11
P neurogenesis 1.4e-14 4.6e-11
P embryonic development 2e-14 5.4e-11
P generation of neurons 4.6e-14 1.1e-10
P pattern specification process 1.7e-13 3.5e-10
P neuron differentiation 2.5e-13 4.5e-10
P anatomical structure morphogenesis 3e-13 4.9e-10
P organ morphogenesis 5.6e-13 8.2e-10
P developmental process 1.2e-12 1.6e-09
P regionalization 2.7e-12 3.4e-09
P central nervous system development 5.4e-12 6.2e-09
P embryonic morphogenesis 1.4e-11 1.6e-08
P cell fate commitment 2.4e-11 2.4e-08
P multicellular organismal process 2.6e-11 2.5e-08
P neuron fate commitment 9.4e-11 8.5e-08
P forebrain development 2.3e-10 2e-07
P cell development 1.2e-09 9.3e-07
P brain development 2.2e-09 1.7e-06
P embryonic organ morphogenesis 6.4e-09 4.7e-06
P cell differentiation 6.7e-09 4.7e-06
P embryonic organ development 7.2e-09 4.9e-06
P neuron development 1.5e-08 9.7e-06
P anatomical structure development 1.8e-08 1.1e-05
P neuron fate specification 2e-08 1.2e-05
P anterior/posterior pattern formation 2.6e-08 1.5e-05
P regulation of nervous system development 5.3e-08 3e-05
P sensory organ development 7.5e-08 4e-05
P skeletal system morphogenesis 1.1e-07 5.9e-05
P cell fate specification 1.7e-07 8.8e-05
P spinal cord development 2.2e-07 0.0001
P cellular developmental process 2.1e-07 0.0001
P embryonic skeletal system development 2.6e-07 0.00012
P cell differentiation in spinal cord 3.1e-07 0.00013
P limb morphogenesis 3e-07 0.00013
P appendage morphogenesis 3e-07 0.00013
P embryonic development ending in birth or egg hatching 3.2e-07 0.00013
P regulation of neurogenesis 3.3e-07 0.00014
P cell morphogenesis involved in neuron differentiation 4.2e-07 0.00016
P chordate embryonic development 4.2e-07 0.00016
P appendage development 5.7e-07 0.00021
P limb development 5.7e-07 0.00021
P extracellular structure organization 8.2e-07 0.0003
P embryonic skeletal system morphogenesis 8.9e-07 0.00031
P axonogenesis 8.9e-07 0.00031
P ventral spinal cord development 1.1e-06 0.00036
P neuron projection morphogenesis 1.4e-06 0.00047
P regulation of neuron differentiation 1.8e-06 0.00059
P ear development 3.2e-06 0.001
P spinal cord motor neuron differentiation 3.6e-06 0.0011
P negative regulation of transcription from RNA polymerase II promoter 5.5e-06 0.0017
P cell morphogenesis involved in differentiation 5.6e-06 0.0017
P neuron projection development 5.9e-06 0.0017
P skeletal system development 1.1e-05 0.0031
P cell projection organization 1.2e-05 0.0033
P embryonic limb morphogenesis 1.2e-05 0.0033
P embryonic appendage morphogenesis 1.2e-05 0.0033
P transmission of nerve impulse 1.9e-05 0.0052
P forelimb morphogenesis 2e-05 0.0052
P positive regulation of transcription from RNA polymerase II promoter 2.3e-05 0.006
P spinal cord motor neuron cell fate specification 2.5e-05 0.0064
P olfactory bulb development 2.6e-05 0.0067
P olfactory lobe development 3.3e-05 0.0083
P localization of cell 3.6e-05 0.0087
P cell motility 3.6e-05 0.0087
P regulation of multicellular organismal process 3.7e-05 0.0088
P cell fate determination 3.7e-05 0.0088
P endocrine system development 3.9e-05 0.009
P positive regulation of transcription 4.6e-05 0.011
P tube morphogenesis 5.4e-05 0.012
P system process 5.5e-05 0.012
P urogenital system development 6e-05 0.013
P regulation of organ growth 6e-05 0.013
P dorsal spinal cord development 6.9e-05 0.015
P proximal/distal pattern formation 7e-05 0.015
P telencephalon development 7.3e-05 0.015
P renal system development 8e-05 0.016
P diencephalon development 8e-05 0.016
P palate development 7.8e-05 0.016
P positive regulation of transcription, DNA-dependent 7.9e-05 0.016
P respiratory system development 8.2e-05 0.016
P axon guidance 8.4e-05 0.016
P synaptic transmission 8.9e-05 0.017
P tissue development 9.4e-05 0.018
P cell migration 9.4e-05 0.018
P lung development 9.6e-05 0.018
P ventral spinal cord interneuron differentiation 0.0001 0.019
P kidney development 0.00011 0.02
P inner ear development 0.00011 0.02
P ear morphogenesis 0.00012 0.021
P respiratory tube development 0.00013 0.023
P embryonic digestive tract morphogenesis 0.00014 0.024
P segment specification 0.00014 0.024
P regulation of cell development 0.00015 0.025
P cell projection morphogenesis 0.00016 0.026
P regulation of cell differentiation 0.00016 0.027
P hindbrain development 0.00017 0.028
P adult locomotory behavior 0.00017 0.028
P positive regulation of RNA metabolic process 0.00018 0.029
P pituitary gland development 0.0002 0.032
P synapse organization 0.0002 0.032
P negative regulation of transcription 0.00022 0.035
P positive regulation of glial cell differentiation 0.00023 0.035
P embryonic forelimb morphogenesis 0.00023 0.035
P branching morphogenesis of a tube 0.00027 0.041
P locomotion 0.00028 0.042
P ventral spinal cord interneuron fate commitment 0.0003 0.044
P negative regulation of neuron apoptosis 0.00031 0.045
P adult behavior 0.00031 0.045
P positive regulation of gliogenesis 0.00033 0.048
P cardiac ventricle morphogenesis 0.00035 0.05
P cell morphogenesis 0.00036 0.051
P cartilage development 0.00037 0.053
P cardiac chamber development 0.00042 0.058
P positive regulation of gene expression 0.00042 0.058
P spinal cord dorsal/ventral patterning 0.00043 0.059
P ventral spinal cord interneuron specification 0.00043 0.059
P tube development 0.00043 0.059
P negative regulation of transcription, DNA-dependent 0.00044 0.059
P heart development 0.00045 0.059
P regulation of transcription from RNA polymerase II promoter 0.00044 0.059
P cardiac chamber morphogenesis 0.00045 0.059
P digestive tract morphogenesis 0.00045 0.059
P regulation of neuron apoptosis 0.0005 0.064
P cell part morphogenesis 0.00051 0.065
P hindlimb morphogenesis 0.00051 0.065
P generation of neurons in the forebrain 0.00053 0.066
P sensory perception of mechanical stimulus 0.00053 0.066
P forebrain neuron differentiation 0.00054 0.067
P regulation of cell proliferation 0.00061 0.075
P regulation of gliogenesis 0.00061 0.075
P glial cell differentiation 0.00068 0.082
P spinal cord patterning 0.00069 0.082
P organ formation 0.00071 0.084
P regulation of chondrocyte differentiation 0.00079 0.094
P oligodendrocyte differentiation 0.00082 0.096
P regulation of respiratory burst 0.00085 0.098
P peripheral nervous system neuron differentiation 0.00085 0.098
P peripheral nervous system neuron development 0.00085 0.098
P extracellular matrix organization 0.00086 0.099
P regulation of developmental process 0.00088 0.1
P ventricular cardiac muscle tissue morphogenesis 0.00092 0.1
P positive regulation of macromolecule biosynthetic process 0.00095 0.11
P cardiac ventricle development 0.0011 0.12
P regulation of axonogenesis 0.0011 0.12
P neuron migration 0.0011 0.12
P heart morphogenesis 0.0011 0.12
P gliogenesis 0.0011 0.12
P olfactory bulb interneuron differentiation 0.0012 0.12
P cardiac right ventricle morphogenesis 0.0012 0.12
P regulation of smoothened signaling pathway 0.0012 0.12
P regulation of glial cell differentiation 0.0012 0.13
P dorsal/ventral pattern formation 0.0012 0.13
P blood vessel development 0.0014 0.15
P heterophilic cell adhesion 0.0014 0.15
P inner ear morphogenesis 0.0015 0.16
P muscle organ development 0.0016 0.16
P exocrine system development 0.0016 0.17
P eye development 0.0017 0.17
P cellular component morphogenesis 0.0017 0.17
P smoothened signaling pathway 0.0018 0.18
P glomerular basement membrane development 0.0018 0.18
P segmentation 0.0019 0.18
P ventricular cardiac muscle tissue development 0.0019 0.18
P vasculature development 0.0019 0.19
P organ growth 0.0019 0.19
P learning 0.0019 0.19
P cell proliferation 0.002 0.19
P negative regulation of gene expression 0.002 0.19
P intracellular signaling pathway 0.002 0.19
P nerve development 0.0021 0.2
P neurotransmitter transport 0.0021 0.2
P neuron apoptosis 0.0022 0.21
P cardiac muscle tissue morphogenesis 0.0023 0.21
P regulation of transcription 0.0023 0.21
P behavior 0.0023 0.21
P regulation of neuron projection development 0.0024 0.22
P blood vessel morphogenesis 0.0025 0.23
P renal system process 0.0026 0.23
P glomerulus development 0.0026 0.23
P positive regulation of glycogen metabolic process 0.0026 0.23
P cranial nerve development 0.0029 0.25
P muscle tissue morphogenesis 0.0029 0.26
P activation of protein kinase A activity 0.0032 0.28
P Wnt receptor signaling pathway 0.0032 0.28
P cellular polysaccharide metabolic process 0.0032 0.28
P ureteric bud morphogenesis 0.0032 0.28
P metencephalon development 0.0032 0.28
P regulation of Wnt receptor signaling pathway 0.0032 0.28
P forebrain neuron fate commitment 0.0033 0.28
P cerebellum development 0.0034 0.28
P morphogenesis of a branching structure 0.0034 0.29
P sensory perception of sound 0.0035 0.29
P somatic stem cell maintenance 0.0036 0.29
P pancreas development 0.0036 0.29
P post-embryonic development 0.0037 0.3
P regulation of glycogen metabolic process 0.0037 0.31
P Wnt receptor signaling pathway through beta-catenin 0.0039 0.31
P behavioral interaction between organisms 0.0039 0.32
P learning or memory 0.0041 0.33
P transcription from RNA polymerase II promoter 0.0042 0.33
P positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 0.0042 0.34
P positive regulation of biosynthetic process 0.0043 0.34
P branching involved in ureteric bud morphogenesis 0.0044 0.34
P cardiac septum development 0.0044 0.34
P cellular polysaccharide biosynthetic process 0.0044 0.35
P positive regulation of cell proliferation 0.0046 0.35
P mesenchyme development 0.0046 0.35
P energy reserve metabolic process 0.0048 0.37
P mesoderm development 0.0048 0.37
P regulation of embryonic development 0.0048 0.37
P positive regulation of neuroblast proliferation 0.0049 0.37
P metanephros development 0.0051 0.37
P ureteric bud development 0.0052 0.37
P Notch signaling pathway 0.0049 0.37
P muscle structure development 0.0051 0.37
P pericardium development 0.0049 0.37
P neurological system process 0.0051 0.37
P positive regulation of cellular biosynthetic process 0.005 0.37
P negative regulation of RNA metabolic process 0.0051 0.37
P hippo signaling pathway 0.0051 0.37
P chondrocyte differentiation 0.0052 0.37
P regulation of carbohydrate catabolic process 0.005 0.37
P regulation of cellular carbohydrate catabolic process 0.005 0.37
P regulation of generation of precursor metabolites and energy 0.005 0.37
P synapse assembly 0.0051 0.37
P cellular response to vitamin A 0.0054 0.38
P cellular response to retinoic acid 0.0054 0.38
P cellular component movement 0.0055 0.38
P bone morphogenesis 0.0055 0.38
P negative regulation of secretion 0.0057 0.39
P regulation of glycogen biosynthetic process 0.0057 0.39
P regulation of glucan biosynthetic process 0.0057 0.39
P regulation of ERK1 and ERK2 cascade 0.0059 0.4
P neuromuscular process controlling balance 0.006 0.41
P development of primary male sexual characteristics 0.0064 0.44
P thymus development 0.0065 0.44
P positive regulation of axonogenesis 0.0066 0.44
P peripheral nervous system development 0.0066 0.44
P gland development 0.0066 0.44
P negative regulation of cellular biosynthetic process 0.0067 0.45
P regulation of oligodendrocyte differentiation 0.0067 0.45
P negative regulation of gliogenesis 0.0068 0.45
P ERK1 and ERK2 cascade 0.007 0.46
P positive regulation of glycogen biosynthetic process 0.0071 0.46
P positive regulation of oligodendrocyte differentiation 0.0071 0.46
P neuromuscular process 0.0071 0.46
P regulation of neurotransmitter levels 0.0071 0.46
P gut development 0.0073 0.47
P negative regulation of macromolecule biosynthetic process 0.0073 0.47
P muscle system process 0.0074 0.47
P regulation of cartilage development 0.0074 0.48
P glycogen metabolic process 0.0075 0.48
P striated muscle tissue development 0.0076 0.48
P anatomical structure formation involved in morphogenesis 0.0076 0.48
P epithelial tube morphogenesis 0.0076 0.48
P branching involved in lung morphogenesis 0.0078 0.49
P endocardial cushion morphogenesis 0.0078 0.49
P muscle tissue development 0.0079 0.49
P tissue morphogenesis 0.0079 0.49
P mesenchymal cell development 0.0079 0.49
P mesenchymal cell differentiation 0.008 0.49
P regulation of cell communication 0.0082 0.5
P mammary gland development 0.0089 0.54
P cellular glucan metabolic process 0.0089 0.54
P gonadotropin secretion 0.0088 0.54
P glucan metabolic process 0.0089 0.54
P smooth muscle contraction 0.009 0.54
P male sex differentiation 0.0093 0.56
P regulation of biosynthetic process 0.0094 0.56
P odontogenesis 0.0095 0.56
P regulation of polysaccharide metabolic process 0.01 0.59
P negative regulation of glial cell differentiation 0.01 0.6
P regulation of cellular biosynthetic process 0.01 0.6
P ionotropic glutamate receptor signaling pathway 0.01 0.6
P specification of organ identity 0.01 0.61
F Ras guanyl-nucleotide exchange factor activity 2.7e-05 0.052
F small GTPase regulator activity 8.2e-05 0.069
F guanyl-nucleotide exchange factor activity 0.00011 0.069
F GTPase regulator activity 0.00052 0.26
F ion channel activity 0.0018 0.37
F extracellular matrix structural constituent 0.0011 0.37
F nucleoside-triphosphatase regulator activity 0.0016 0.37
F passive transmembrane transporter activity 0.002 0.37
F calcium ion binding 0.0012 0.37
F glutamate receptor binding 0.0023 0.37
F substrate-specific channel activity 0.0021 0.37
F channel activity 0.0019 0.37
F neurotransmitter transporter activity 0.0034 0.51
F PDZ domain binding 0.0042 0.55
F neurotransmitter:sodium symporter activity 0.004 0.55
F Rho guanyl-nucleotide exchange factor activity 0.0048 0.57
F receptor binding 0.0049 0.57
F metal ion binding 0.0073 0.72
F gated channel activity 0.0072 0.72
F beta-catenin binding 0.0069 0.72
F microfilament motor activity 0.0087 0.78
F secondary active transmembrane transporter activity 0.0085 0.78
F cation channel activity 0.0097 0.83
C plasma membrane part 7.1e-09 1.2e-05
C intrinsic to plasma membrane 2.6e-06 0.0022
C integral to plasma membrane 2.3e-05 0.013
C proteinaceous extracellular matrix 3.2e-05 0.014
C plasma membrane 4.8e-05 0.016
C cell projection 0.00017 0.049
C basal lamina 0.00033 0.081
C basement membrane 0.00068 0.12
C postsynaptic membrane 0.00069 0.12
C extracellular matrix part 0.00076 0.12
C neuron projection 0.0007 0.12
C extracellular matrix 0.00087 0.12
C neuronal cell body 0.0011 0.15
C cell body 0.0013 0.16
C cell junction 0.0019 0.22
C myosin complex 0.0021 0.23
C cation channel complex 0.0033 0.27
C brush border 0.0032 0.27
C axonal growth cone 0.0032 0.27
C growth cone 0.0033 0.27
C synapse 0.0027 0.27
C receptor complex 0.004 0.31
C brush border membrane 0.0048 0.35
C site of polarized growth 0.006 0.43
C axon 0.0064 0.44
C ionotropic glutamate receptor complex 0.0073 0.48
C anchored to membrane 0.0087 0.55
C axoneme 0.0092 0.56