P cellular metabolic process 1.5e-11 5.7e-07 P cellular macromolecule biosynthetic process 1.2e-10 2.4e-06 P biosynthetic process 8e-10 6.1e-06 P gene expression 1.1e-09 6.1e-06 P macromolecule biosynthetic process 7.6e-10 6.1e-06 P cellular biosynthetic process 6e-10 6.1e-06 P metabolic process 9.8e-10 6.1e-06 P nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 5.6e-08 0.00027 P transcription 8.3e-07 0.0036 P regulation of gene expression 1e-06 0.004 P RNA metabolic process 9.6e-06 0.034 P RNA processing 1.9e-05 0.058 P cellular macromolecule metabolic process 1.8e-05 0.058 P mRNA metabolic process 3.3e-05 0.092 P regulation of transcription 3.9e-05 0.1 P regulation of macromolecule biosynthetic process 6.9e-05 0.17 P protein modification by small protein conjugation 9.9e-05 0.23 P proteasomal ubiquitin-dependent protein catabolic process 0.0001 0.23 P ribonucleoprotein complex biogenesis 0.00019 0.39 P regulation of cellular biosynthetic process 0.00024 0.48 P proteasomal protein catabolic process 0.00027 0.5 P regulation of biosynthetic process 0.00032 0.56 P protein ubiquitination 0.00046 0.78 P modification-dependent macromolecule catabolic process 0.0062 1 P regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 0.00069 1 P modification-dependent protein catabolic process 0.0061 1 P rRNA processing 0.0014 1 P energy derivation by oxidation of organic compounds 0.0049 1 P cellular protein complex disassembly 0.0062 1 P post-Golgi vesicle-mediated transport 0.0028 1 P posttranscriptional regulation of gene expression 0.008 1 P protein modification by small protein conjugation or removal 0.0015 1 P macromolecule metabolic process 0.00096 1 P nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 0.0033 1 P Golgi vesicle transport 0.00096 1 P ATP synthesis coupled electron transport 0.01 1 P viral transcription 0.0036 1 P mitochondrial respiratory chain complex assembly 0.0076 1 P RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 0.0019 1 P cofactor biosynthetic process 0.0049 1 P Golgi organization 0.007 1 P electron transport chain 0.003 1 P respiratory electron transport chain 0.0044 1 P nuclear-transcribed mRNA catabolic process 0.00068 1 P RNA splicing, via transesterification reactions 0.0014 1 P primary metabolic process 0.00064 1 P mitochondrial translational elongation 0.01 1 P ribosome biogenesis 0.0014 1 P mitochondrial translational termination 0.004 1 P ubiquitin-dependent protein catabolic process 0.0082 1 P ncRNA processing 0.0014 1 P DNA replication 0.0028 1 P mitochondrial translation 0.002 1 P RNA catabolic process 0.00074 1 P mRNA catabolic process 0.00076 1 P rRNA metabolic process 0.0013 1 P translational initiation 0.0035 1 P mitotic cell cycle 0.0076 1 P cell cycle 0.0076 1 P cellular macromolecular complex disassembly 0.0032 1 P translational termination 0.0031 1 P RNA splicing 0.0023 1 P mRNA processing 0.0058 1 P nuclear mRNA splicing, via spliceosome 0.0019 1 P cellular respiration 0.0032 1 P cellular macromolecule catabolic process 0.0059 1 P transcription, DNA-dependent 0.0022 1 P cotranslational protein targeting to membrane 0.0017 1 P SRP-dependent cotranslational protein targeting to membrane 0.0033 1 P protein targeting to ER 0.002 1 P protein homooligomerization 0.0038 1 F protein binding 2e-12 1.4e-08 F binding 4.6e-08 0.00016 F metal ion binding 8.4e-05 0.19 F cation binding 0.00027 0.45 F nucleotide binding 0.00037 0.5 F structural constituent of ribosome 0.00065 0.74 F purine nucleotide binding 0.0054 1 F GTP binding 0.0071 1 F guanyl nucleotide binding 0.0096 1 F purine ribonucleotide binding 0.0051 1 F ribonucleotide binding 0.0081 1 F catalytic activity 0.0047 1 C intracellular part 1.9e-43 8.3e-40 C intracellular 1.6e-40 3.5e-37 C intracellular membrane-bounded organelle 5e-40 7.3e-37 C intracellular organelle 1.2e-33 1.3e-30 C membrane-bounded organelle 6.9e-33 6.1e-30 C organelle 3.9e-27 2.8e-24 C nucleus 4.9e-24 3e-21 C cytoplasm 9.5e-24 5.2e-21 C intracellular organelle part 1.2e-20 5.6e-18 C cytoplasmic part 2.6e-20 1.1e-17 C organelle part 2.8e-19 1.1e-16 C nuclear part 2.2e-16 8e-14 C nucleoplasm 2.8e-13 9.4e-11 C intracellular organelle lumen 5.1e-13 1.6e-10 C membrane-enclosed lumen 2.3e-12 6.7e-10 C cytosol 5.2e-12 1.4e-09 C organelle lumen 8.6e-12 2.2e-09 C mitochondrion 4e-11 9.8e-09 C nuclear lumen 9.4e-11 2.2e-08 C mitochondrial part 4.7e-09 1e-06 C cell part 5.5e-08 1.1e-05 C cell 1.4e-07 2.8e-05 C organelle envelope 1.9e-07 3.6e-05 C envelope 2.9e-07 5.2e-05 C mitochondrial envelope 1.5e-06 0.00027 C organelle membrane 1.7e-06 0.00029 C mitochondrial lumen 3.3e-06 0.00052 C mitochondrial matrix 3.3e-06 0.00052 C mitochondrial membrane 6.5e-06 0.00097 C organelle inner membrane 1e-05 0.0014 C mitochondrial inner membrane 1e-05 0.0014 C nucleolus 2.2e-05 0.003 C ribonucleoprotein complex 5.3e-05 0.0071 C ribosomal subunit 0.00033 0.042 C ribosome 0.00051 0.064 C mitochondrial membrane part 0.0018 0.21 C centrosome 0.002 0.24 C nuclear body 0.0032 0.37 C ubiquitin ligase complex 0.0038 0.43 C nucleoplasm part 0.0039 0.43 C focal adhesion 0.0046 0.49 C cell-substrate adherens junction 0.0048 0.5 C adherens junction 0.005 0.51 C organelle envelope lumen 0.006 0.51 C organellar ribosome 0.0053 0.51 C cell-substrate junction 0.0058 0.51 C Golgi membrane 0.006 0.51 C large ribosomal subunit 0.0059 0.51 C mitochondrial ribosome 0.0053 0.51 C spliceosomal complex 0.0058 0.51 C anchoring junction 0.0054 0.51 C nuclear speck 0.006 0.51 C endoplasmic reticulum membrane 0.0065 0.54 C nuclear envelope-endoplasmic reticulum network 0.0068 0.55 C microtubule organizing center 0.0089 0.71 C mitochondrial intermembrane space 0.01 0.79 C nuclear envelope 0.01 0.8