P system process 1.5e-17 3.7e-13 P neurological system process 2.8e-16 3.5e-12 P detection of stimulus involved in sensory perception 3.8e-13 1.9e-09 P detection of chemical stimulus 2.5e-13 1.9e-09 P sensory perception of chemical stimulus 3.6e-13 1.9e-09 P cognition 6.8e-13 2.8e-09 P detection of chemical stimulus involved in sensory perception 1.2e-12 3.6e-09 P sensory perception of smell 1.1e-12 3.6e-09 P sensory perception 2.3e-12 6.5e-09 P G-protein coupled receptor protein signaling pathway 3.4e-12 8.4e-09 P detection of chemical stimulus involved in sensory perception of smell 4.3e-12 9.8e-09 P detection of stimulus 3.2e-11 6.6e-08 P multicellular organismal process 3.6e-09 6.9e-06 P homophilic cell adhesion 3.6e-08 6.5e-05 P transmission of nerve impulse 7.5e-08 0.00012 P synaptic transmission 1.5e-06 0.0024 P G-protein signaling, coupled to cyclic nucleotide second messenger 6.9e-05 0.1 P cyclic-nucleotide-mediated signaling 0.00014 0.19 P G-protein signaling, coupled to cAMP nucleotide second messenger 0.00023 0.29 P cAMP-mediated signaling 0.00038 0.47 P cytosolic calcium ion homeostasis 0.00048 0.57 P calcium-dependent cell-cell adhesion 0.00083 0.94 P defense response to bacterium 0.00088 0.95 P multicellular organismal catabolic process 0.0071 1 P cell recognition 0.0014 1 P serotonin receptor signaling pathway 0.007 1 P regulation of tube size 0.0033 1 P inhibition of adenylate cyclase activity by G-protein signaling pathway 0.0086 1 P activation of adenylate cyclase activity by serotonin receptor signaling pathway 0.0055 1 P retina morphogenesis in camera-type eye 0.0029 1 P dopamine metabolic process 0.0073 1 P collagen catabolic process 0.0026 1 P regulation of dopamine secretion 0.006 1 P elevation of cytosolic calcium ion concentration 0.0054 1 P response to tropane 0.0029 1 P dopamine secretion 0.006 1 P multicellular organismal macromolecule metabolic process 0.0047 1 P neurotransmitter transport 0.0048 1 P response to amphetamine 0.0026 1 P regulation of cAMP biosynthetic process 0.0025 1 P regulation of cAMP metabolic process 0.0035 1 P regulation of blood pressure 0.006 1 P muscle contraction 0.0095 1 P regulation of nucleotide biosynthetic process 0.0052 1 P regulation of cyclic nucleotide biosynthetic process 0.0026 1 P regulation of interleukin-18 production 0.0074 1 P immune response 0.0056 1 P regulation of adenylate cyclase activity 0.0016 1 P cAMP metabolic process 0.0026 1 P ovulation from ovarian follicle 0.0083 1 P cellular calcium ion homeostasis 0.0011 1 P circulatory system process 0.0067 1 P vascular process in circulatory system 0.0053 1 P vasoconstriction 0.0052 1 P regulation of atrial cardiomyocyte membrane depolarization 0.0083 1 P regulation of cyclic nucleotide metabolic process 0.0024 1 P positive regulation of vasodilation 0.0087 1 P dopamine transport 0.0073 1 P regulation of blood vessel size 0.003 1 P cyclic nucleotide metabolic process 0.0028 1 P calcium ion homeostasis 0.0023 1 P nerve-nerve synaptic transmission 0.0027 1 P adaptive immune response 0.0079 1 P cyclic nucleotide biosynthetic process 0.007 1 P synapse assembly 0.01 1 P extracellular structure organization 0.0021 1 P hormone metabolic process 0.0083 1 P regulation of lyase activity 0.0019 1 P collagen metabolic process 0.0045 1 P response to cocaine 0.0029 1 P cAMP biosynthetic process 0.003 1 P regulation of cyclase activity 0.0015 1 P defense response 0.0083 1 P blood circulation 0.0055 1 F transmembrane receptor activity 3e-16 1.1e-12 F G-protein coupled receptor activity 5.7e-16 1.1e-12 F receptor activity 4.1e-15 5.1e-12 F olfactory receptor activity 3e-12 2.8e-09 F signal transducer activity 6e-12 3.8e-09 F molecular transducer activity 6e-12 3.8e-09 F calcium ion binding 2.8e-11 1.5e-08 F gated channel activity 3.7e-05 0.017 F monooxygenase activity 4e-05 0.017 F ion channel activity 8.3e-05 0.031 F substrate-specific channel activity 0.00019 0.064 F passive transmembrane transporter activity 0.00047 0.14 F channel activity 0.00044 0.14 F carbohydrate binding 0.00055 0.15 F tetrapyrrole binding 0.00078 0.2 F amine binding 0.00084 0.2 F cation channel activity 0.00091 0.2 F extracellular matrix structural constituent 0.001 0.22 F oxygen binding 0.0012 0.23 F ligand-gated channel activity 0.0016 0.28 F ligand-gated ion channel activity 0.0016 0.28 F heme binding 0.0022 0.36 F peptide receptor activity, G-protein coupled 0.0021 0.36 F peptide receptor activity 0.0024 0.37 F glycosaminoglycan binding 0.0035 0.53 F steroid hydroxylase activity 0.004 0.58 F calcium-activated potassium channel activity 0.0046 0.63 F glutamate receptor activity 0.0048 0.64 F calmodulin binding 0.0051 0.64 F ion gated channel activity 0.005 0.64 F serotonin receptor activity 0.007 0.74 F substrate-specific transmembrane transporter activity 0.0066 0.74 F pattern recognition receptor activity 0.0068 0.74 F neurotransmitter binding 0.0066 0.74 F transmembrane transporter activity 0.0067 0.74 F potassium channel activity 0.0071 0.74 F protein-arginine deiminase activity 0.0074 0.75 F excitatory extracellular ligand-gated ion channel activity 0.0076 0.76 F odorant binding 0.0079 0.76 F polysaccharide binding 0.0093 0.78 F pattern binding 0.0093 0.78 F G-protein coupled amine receptor activity 0.0091 0.78 F oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 0.0087 0.78 F neuropeptide binding 0.0088 0.78 F voltage-gated cation channel activity 0.0094 0.78 F arachidonic acid epoxygenase activity 0.01 0.81 F arachidonic acid monooxygenase activity 0.01 0.81 F extracellular ligand-gated ion channel activity 0.01 0.81 C intrinsic to membrane 4.7e-17 1.1e-13 C integral to membrane 2.8e-16 3.3e-13 C integral to plasma membrane 1.6e-15 1.3e-12 C intrinsic to plasma membrane 1.2e-14 7.2e-12 C plasma membrane 2.3e-14 1.1e-11 C membrane part 5.5e-10 2.2e-07 C plasma membrane part 9.7e-10 3.3e-07 C proteinaceous extracellular matrix 2.7e-05 0.0079 C extracellular region 0.00011 0.025 C intermediate filament 0.00011 0.025 C intermediate filament cytoskeleton 0.00012 0.026 C extracellular matrix part 0.00055 0.11 C acrosomal vesicle 0.00061 0.11 C extracellular matrix 0.0011 0.18 C apical plasma membrane 0.0016 0.25 C perikaryon 0.0025 0.3 C keratin filament 0.0021 0.3 C apical part of cell 0.0025 0.3 C cell surface 0.0025 0.3 C contractile fiber 0.0024 0.3 C collagen 0.0027 0.3 C myofibril 0.003 0.32 C fibrillar collagen 0.0039 0.38 C receptor complex 0.004 0.38 C contractile fiber part 0.0038 0.38 C cation channel complex 0.0046 0.41 C sarcomere 0.0047 0.41 C axon terminus 0.0056 0.47 C extracellular space 0.0063 0.51 C postsynaptic membrane 0.0066 0.52 C secretory granule 0.0075 0.55 C neuron projection terminus 0.0073 0.55 C membrane 0.0079 0.56 C neuron projection 0.0098 0.69